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      <title>Der asthmatische Sportler: Metabolische und ventilatorische Reaktionen auf Belastung mit und ohne Medikation vor Belastung</title>
      <pubDate>Wed, 01 Jan 1997 14:14:40 +0100</pubDate>
      <link>https://sponet.de/sponet/Record/4003585</link>
      <guid>https://sponet.de/sponet/Record/4003585</guid>
      <author>Ienna, T. M.</author>
      <author>McKenzie, D. C.</author>
      <dc:format>Artikel</dc:format>
      <dc:subject>Atmung</dc:subject>
      <dc:subject>Belastung</dc:subject>
      <dc:subject>Krankheit</dc:subject>
      <dc:subject>Organ</dc:subject>
      <dc:subject>Pharmaka</dc:subject>
      <dc:subject>Stoffwechsel</dc:subject>
      <dc:subject>Therapie</dc:subject>
      <dc:subject>Sportmedizin</dc:subject>
      <dc:format>Artikel</dc:format>
      <dc:creator>Ienna, T. M.</dc:creator>
      <dc:creator>McKenzie, D. C.</dc:creator>
      <content:encoded><![CDATA[To determine whether asthmatic athletes have normal physiological responses to exercise without pre-exercise medication, we studied 17 female and male asthmatic subjects, 9 highly trained (HT) and 8 moderately trained (MT) under 2 conditions: salbutamol (S) 200 micrograms taken via inhaler 15 minutes prior to exercise or placebo (PL). The exercise task was 4 continuous 5 minute increments representing 25, 50, 75 and 90% of the subject's VO2max.VO2, minute ventilation (VE), respiratory exchange ratio (RER), % saturation (SaO2), and HR were continuously measured during exercise. Blood lactate (LA) was measured each minute throughout exercise and recovery. Post-medication, exercise, and recovery measurements of peak expiratory flow rates (PEFR) were made using a Mini-Wright flow meter. No differences (p > 0.05) between treatment conditions were found at any stage of exercise with respect to VO2, VE, RER, HR and SaO2. However, among the HT group the mean HR for the 4 exercise conditions was significantly higher under PL (PL = 151.7;S = 147.2; p = 0.01). No difference was found in LA during exercise or in recovery. Pre-exercise PEFR was significantly higher when pretreatment was S(S = 582; PL = 545 l.sec-1; p = 0.003). During the exercise and recovery conditions mean PEFR measures were significantly higher (S = 600.1; PL = 569.6; p = 0.002) with the S treatment. Bonferroni's test detected a difference in PEFR measures between S and PL at 25% and 50% VO2max and 3 and 15 minutes into recovery. There was no difference in the physiological response to exercise between groups based on training status. It was concluded that although S affects the PEFR these asthmatic athletes do not have altered metabolic or ventilatory responses during this incremental exercise protocol.]]></content:encoded>
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    <item>
      <title>Der asthmatische Sportler: Stoffwechsel- und Atmungsreaktionen auf Belastung mit und ohne Medikation vor Belastung</title>
      <pubDate>Wed, 01 Jan 1997 14:14:40 +0100</pubDate>
      <link>https://sponet.de/sponet/Record/3026343</link>
      <guid>https://sponet.de/sponet/Record/3026343</guid>
      <author>Ienna, T. M.</author>
      <author>McKenzie, D. C.</author>
      <dc:format>Artikel</dc:format>
      <dc:subject>Sportmedizin</dc:subject>
      <dc:subject>Krankheit</dc:subject>
      <dc:subject>Atmung</dc:subject>
      <dc:subject>Organ</dc:subject>
      <dc:subject>Pharmaka</dc:subject>
      <dc:subject>Therapie</dc:subject>
      <dc:subject>Sportphysiologie</dc:subject>
      <dc:subject>Stoffwechsel</dc:subject>
      <dc:subject>Funktion</dc:subject>
      <dc:subject>Belastung</dc:subject>
      <dc:format>Artikel</dc:format>
      <dc:creator>Ienna, T. M.</dc:creator>
      <dc:creator>McKenzie, D. C.</dc:creator>
      <content:encoded><![CDATA[Zielstellung: Untersuchung, ob asthmatische Sportler ohne Medikation vor Belastung normale physiologische Reaktionen auf Belastung zeigen.
Probanden/Methoden:17 weibliche und männliche asthmatische Probanden, 9 hochtrainierte (HT) und 8 moderat trainierte (MT), wurden unter zwei Bedingungen untersucht: Inhalation von 200 Milligramm Salbutamol (S)oder Placebo (PL) 15 min vor Belastung. Die Belastung bestand aus 4 ansteigenden 5minütigen Fahrradergometertests mit jeweils einer Belastung von 25, 50, 75 und 90% der VO2max. Während der Belastung wurden VO2, VE, RER, %SaO2 und HF gemessen, Laktat während und nach Belastung. Ergebnis: Es lagen keine unterschiedlichen physiologischen Reaktionen auf Belastung zwischen den beiden Gruppen vor. Obwohl Salbutamol die Höhe der maximalen expiratorischen Atemstromstärke beeinflußt, haben die asthmatischen Sportler keine veränderten Stoffwechsel- oder Atmungsreaktionen während des ansteigenden Belastungstests.]]></content:encoded>
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