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    <item>
      <title>Der Serumoxidansstatus in Ruhe korreliert positiv mit der maximalen Sauerstoffaufnahme bei ausdauertrainierten Läufern</title>
      <pubDate>Fri, 01 Jan 1999 11:33:27 +0100</pubDate>
      <link>https://sponet.de/sponet/Record/4004251</link>
      <guid>https://sponet.de/sponet/Record/4004251</guid>
      <author>Child, R. B.</author>
      <author>Wilkinson, D. M.</author>
      <author>Fallowfield, J. L.</author>
      <dc:format>Artikel</dc:format>
      <dc:subject>Antioxidans</dc:subject>
      <dc:subject>Ausdauer</dc:subject>
      <dc:subject>maximal</dc:subject>
      <dc:subject>O2-Aufnahme</dc:subject>
      <dc:subject>Training</dc:subject>
      <dc:format>Artikel</dc:format>
      <dc:creator>Child, R. B.</dc:creator>
      <dc:creator>Wilkinson, D. M.</dc:creator>
      <dc:creator>Fallowfield, J. L.</dc:creator>
      <content:encoded><![CDATA[BACKGROUND: This study tested the hypothesis that the ability to scavenge free radicals in serum was compromised in trained runners. METHODS: Experimental design: peak VO2, the ability to scavenge free radicals in serum and the plasma concentration of malondialdehyde (MDA) were assessed in 18 male runners. Participants: subject characteristics (mean +/- SEM) were height 1.77 +/- 0.01 m, mass 71.4 +/- 1.2 kg, age 31 +/- 1 years and weekly training distance 45 +/- 5 km.week-1. Measures: venous blood samples were collected at rest. Serum total antioxidant capacity (TAC) was determined using a chemiluminescent technique. This involved the oxidation of luminol, in a reaction catalysed by horseradish peroxidase. Serum antioxidant protection was quantified relative to a soluble vitamin E analogue (Trolox) and expressed as Trolox equivalents (Trolox Eq.). MDA was determined using a highly specific assay, using HPLC with fluorimetric detection. Peak VO2 was determined from expired gas measurements collected during an incremental running test on a motorised treadmill. Data were analysed using Pearson correlations. RESULTS: Serum TAC was 500 +/- 26 mumol Trolox Eq.l-1, with a plasma MDA concentration of 1.5 +/- 0.1 mmol.l-1 and serum urate concentration of 274 +/- 12 mmol.l-1. Peak VO2 was 63 +/- 1 ml.kg-1.min-1. Significant correlations were observed between peak VO2 and serum TAC (r = 0.365, p < 0.05); peak VO2 and serum urate (r = 0.463, p < 0.05) and serum urate and serum TAC (r = 0.807, p < 0.001). Plasma MDA and serum TAC were not significantly correlated (r = 0.026, p > 0.05). CONCLUSIONS: These data demonstrate that the ability to quench free radicals in serum in increased in relation to the maximum ability to consume oxygen, however this response does not appear to provide any additional protection against peroxidative damage at rest.]]></content:encoded>
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    <item>
      <title>Der Ruhe-Serumantioxidanzienstatus korreliert positiv mit dem VO2max bei Ausdauer trainierten Läufern</title>
      <pubDate>Fri, 01 Jan 1999 11:33:27 +0100</pubDate>
      <link>https://sponet.de/sponet/Record/3031287</link>
      <guid>https://sponet.de/sponet/Record/3031287</guid>
      <author>Child, R. B.</author>
      <author>Wilkinson, D. M.</author>
      <author>Fallowfield, J. L.</author>
      <dc:format>Artikel</dc:format>
      <dc:subject>Ausdauerdisziplinen</dc:subject>
      <dc:subject>Lauf</dc:subject>
      <dc:subject>Biochemie</dc:subject>
      <dc:subject>Sportphysiologie</dc:subject>
      <dc:subject>O2-Aufnahme</dc:subject>
      <dc:subject>maximal</dc:subject>
      <dc:subject>Antioxidans</dc:subject>
      <dc:format>Artikel</dc:format>
      <dc:creator>Child, R. B.</dc:creator>
      <dc:creator>Wilkinson, D. M.</dc:creator>
      <dc:creator>Fallowfield, J. L.</dc:creator>
      <content:encoded><![CDATA[Es wurde die Hypothese untersucht, daß die Fähigkeit, freie Radikale im Blut zu bereinigen, bei trainierten Läufen beeinträchtigt ist.
18 Läufer waren an den Untersuchungen beteiligt.
Die erhobenen Daten zeigen, dass die Fähigkeit, freie Radikale im Serum zu zerstören, erhöht ist - in Relation zur maximalen O2-Aufnahme-Fähigkeit. Dennoch scheint diese Reaktion keinen zusätzlichen Schutz gegen peroxidative Schäden in Ruhe darzustellen.]]></content:encoded>
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