(1) Background: The use of wearable technology for assessing running biomechanics in field-based sports has increased in recent years. Inertial measurement units (IMUs) are low-cost, non-invasive devices capable of estimating spatiotemporal gait-related metrics during overground locomotion. This study evaluated the accuracy and concurrent validity of a foot-mounted IMU system for estimating sprinting kinematics. (2) Method: Twenty-five elite and sub-elite athletes completed four maximal 10-metre fly efforts, with their kinematics measured concurrently using a three-dimensional motion analysis system and IMUs. (3) Result: The foot-mounted IMU system`s root mean square errors for stride length and duration were 0.22 m and 0.04 s, respectively. Mean biases (95% level of agreement) were -0.67 m · s-1 (-1.19; -0.14) for peak velocity, -0.51 m · s-1 (-1.10; 0.09) for instantaneous velocity, and 0.17 m · s-2 (-1.04; 1.37) for instantaneous acceleration. Stride length, duration, and cadence were -0.07 m (-0.36; 0.23), 0.02 s (-0.02; 0.06), and -4.64 strides · min-1 (-15.82; 6.53), respectively. (4) Conclusions: End users implementing this technology in research and practice should interpret this study`s findings relative to their analytical objectives, logistical resources, and operational constraints. Therefore, its adoption should be guided by the specific performance metrics of interest and the extent to which the system`s capabilities align with the outcomes the end user aims to achieve.
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